Syracuse vs. Virginia odds, prediction, line: Week 4 2022 college football picks by model in run 51-43

JMA Wireless Dome shows a conference fight on Friday night. The Virginia Cavaliers visit the Syracuse Orange in the sixth-ever matchup between the ACC opponents. Virginia is 2-1 and playing their first conference game of the 2022 season. Syracuse is 3-0, including a 1-0 mark in conference play, and the Orange are trying to keep from slipping after three games against Virginia.

Caesars Sportsbook lists the orange as a 10-point home favorite for this 7 p.m. ET opener. The total points Vegas believes will be scored, or the over/under, is 53.5 in the latest Syracuse vs. Virginia odds. Before you make your choice between Virginia and Syracuse, you need to look at SportsLine’s advanced computer simulation model for college football predictions and betting recommendations.

The SportsLine projection model simulates every FBS college football game 10,000 times. For the last 6+ years, the proprietary computer model has racked up a staggering $3,300+ win for $100 players using its top-flight college football picks against the spread. It goes into Week 4 of the 2022 college football season with a 51-43 run on all the top-flight college football spreads and money line picks going back to 2021. Anyone who has followed it has seen tremendous returns.

Now the model has set its sights on Virginia vs. Syracuse and just laid out its picks and CFB predictions. You can now go to SportsLine to see the model selection. Well here are several college football odds and betting lines for Syracuse vs UVA:

  • Spread between Virginia and Syracuse: Syracuse -10
  • Virginia vs. Syracuse Over/Under: 53.5 points
  • Money line between Virginia and Syracuse: Syracuse -385, Virginia +300
  • VIR: The Cavaliers are 7-8 against the range in their last 15 games
  • SYR: The Oranges are 11-4 against the spread in their last 15 games
  • Virginia vs. Syracuse picks: See picks here

Featured Game | Syracuse Orange vs. Virginia Cavaliers

Why Virginia can cover

Virginia’s offense has sky-high benefits. The Cavaliers have surpassed 500 yards in two out of three games this season, and Virginia has a strong ground attack. Virginia averages nearly 180 rushing yards per game and 4.6 yards per carry, with quarterback Brennan Armstrong bringing in a dual threat element. Armstrong has more than 1,000 career rushing yards and he’s coming off a 2021 season that included 4,449 passing yards and 31 touchdowns.

Externally, Virginia has an intriguing and dynamic threat in Keytaon Thompson. He caught 78 passes for 990 yards last season and has 18 catches for 235 yards in three games in 2021. Thompson also rushed for 230+ yards with 39 carries in 2021, and he’s difficult to contain for opposing defenses. Virginia also faces a Syracuse defense that allows for a 73.5% completion rate in three games, and the Cavaliers are well trained and won’t be overwhelmed by the Syracuse street environment.

Why Syracuse can cover

Syracuse’s 2022 season was impressive on both sides of the ball. The Orange are producing at a high level on offense and the Syracuse defense have a potential friendly on Friday. Syracuse is yielding just 16.7 points per game this season, and opponents are averaging just 98.3 rushing yards per game against the Orange. Virginia also scuffles significantly when it comes to putting points on the board.

The Cavaliers are averaging just 17.7 points per game, with just 19 points in their last two games. Virginia had just three points against Illinois and 16 points against Old Dominion, and the Cavaliers rushed for just 222 yards with three turnovers against Illinois. For the season, Virginia completed just 51.9% of pass attempts with more interceptions than touchdowns. The Cavaliers are also the second worst among ACC clubs with a third down conversion rate of just 32.6% in three games.

How to make Virginia vs. Syracuse picks

SportsLine’s model is based on total points, with both teams expected to throw at least one interception. The model also says that one side of the variance is true in almost 60% of the simulations. You can only see the model’s CFB picks at SportsLine.

So who will win Virginia vs Syracuse? And which side of the spread is correct in almost 60% of the simulations? Visit SportsLine now to see which side of the Virginia vs. Syracuse spread you need to jump to on Friday, all from the model who smashed his college football picks and find out.

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