Kansas vs. Duke Odds, Line, Spread: 2022 College Football Pick, Week 4 Predictions Using Proven Model

The Kansas Jayhawks and Duke Blue Devils are both looking to go undefeated on Saturday. Kansas has already surpassed its winning total from last season and made its first 3-0 start since 2009. Duke has looked after business in his first three games, beating his opponents 45-0 overall in the first few quarters of the game.

Kick-off is set for noon ET. The Jayhawks are seven-point favorites in the latest Kansas vs. Duke odds from Caesars Sportsbook while the over/under is fixed at 65. Before participating in Duke vs. Kansas tips, be sure to check out college football predictions from the advanced computer model at SportsLine.

The SportsLine projection model simulates every FBS college football game 10,000 times. For the last 6+ years, the proprietary computer model has racked up a staggering $3,300+ win for $100 players using its top-flight college football picks against the spread. It goes into Week 4 of the 2022 college football season with a 51-43 run on all the top-flight college football spreads and money line picks going back to 2021. Anyone who has followed it has seen tremendous returns.

Now the model has Kansas vs. Duke in her sights. You can go to SportsLine to see the selection. Here are some college football odds for Kansas vs. Duke:

  • Distribution Kansas vs. Duke: Kansas -7
  • Kansas vs. Duke over/under: 65 points
  • Pick Kansas vs. Duke: See picks here

Featured Game | Kansas Jayhawks versus Duke Blue Devils

Why Kansas can cover

Kansas got off to their best start since 2009 and will have a rowdy crowd on hand for Saturday’s game. The Jayhawks pulled up surprises in back-to-back weeks in West Virginia and Houston, giving them a ton of momentum on their return home for the first time since Week 1. They have 48+ points in all three wins and rank fifth nationally in points per game.

Quarterback Jalon Daniels contributed a lot to that success, as he scored five touchdowns in last week’s win over Houston. Daniels has threw for 566 yards and seven touchdowns while also rushing 27 times for 237 yards and three points. Kansas has covered the spread in six straight games, and Duke has covered just once in their last nine road games.

Why Duke can cover

Duke doesn’t get as much attention as Kansas in this game, but the Blue Devils made a solid 3-0 start. They shut out Temple in Week 1 before adding wins over Northwestern and North Carolina A&T in the last two weeks. Quarterback Riley Leonard was efficient, completing 72.7% of his passes for 723 yards and five touchdowns.

Leonard, like Daniels, gives his team an additional rushing threat as he has 147 yards and two touchdowns on the ground. The Blue Devils clinched a 52-33 win when those teams met last season, so this is a valuable spot as big underdogs.

How to do Kansas vs. Duke picks

The model ran Duke vs. Kansas 10,000 times and the results are in. We can tell you that the model is leaning forward and it also generated a point spread pick that hits in almost 60% of the simulations. You can only see the selection at SportsLine.

So who will win Kansas vs. Duke? And which side of the spread is correct in almost 60% of the simulations? Visit SportsLine now to find out which side of the Duke vs. Kansas spread to jump on Saturday, all from the model who crushed his college football picks and find out.

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